Alternative to Liquid Nitrogen

By - Mark
23.05.25 01:50 PM
Hydrozid® is a portable and convenient alternative to liquid nitrogen, with proven effectiveness in treating warts, condylomas, seborrheic keratosis, actinic keratosis, and other benign-, pre-malignant-, and special mucosal lesions. Hydrozid® is used across the World by General Practitioners, Paediatricians, Dermatologists, Podiatrists, Urologists, and Gynaecologists. 

The Hydrozid® technology includes a lightweight, portable canister, which prevents evaporation. The modern Scandinavian design emphasises functionality and ergonomics and makes it easy to use. 

The Danish specialty medical device company BIBAWO Medical A/S has developed Hydrozid® in response to practitioners’ requests for a safe and effective cryosurgery solution. Hydrozid® is CE-marked, CDSCO approved, and FDA cleared, meaning it has been assessed to meet high safety- and quality requirements established by the EU, India, and the USA. 

The Hydrozid® pharma-grade cryo-gas has been used in asthma inhalers for decades, and it is nontoxic and non-flammable. Once the canister is empty, it can be discarded in normal household waste.

Benefits of Hydrozid® 

Hydrozid® eliminates the need for time-consuming preparation procedures, waste of gas through evaporation, and the personal protective equipment that is otherwise associated with cryosurgery for instance when using liquid nitrogen. The practitioner can focus on the patient and the treatment, instead of preparations and how to use the equipment. 

In brief, Hydrozid® is:

Simple

  • Self-contained in a light, portable canister with no evaporation, 
  • No preparation needed, always ready to use, 
  • Just point and spray directly on the lesion. 

Effective

  • Consistent delivery temperature at -54°C. 
  • Less than 30 second treatment time for most common skin lesions.
  • The patented spray head secures exceptional control over the delivery of the cryo-gas. 

Safe

  • No protection equipment required, and can easily be transported in a car² 
  • The cryo-gas is safe for patients and practitioners, 
  • Delivers consistent freezing temperature, and the recommended freeze-thaw method, offers control of the skin while treatment is in progress, reducing the risk of causing skin damage.

Moreover, Hydrozid® is cost effective. There is no waste as there is 3-year’s manufacturing shelf-life at room temperature, and there is no capital investment, making Hydrozid® ideal for both established and new practitioners in clinics and hospitals. 


References:


1. The target temperature for the destruction of benign cells is between -20°C to -30°C and for pre-malignant cells, temperatures of -40°C to -50°C are necessary for destruction. Prohaska J, Badri T. Cryotherapy: Treasure Island (FL): StatPearls Publishing; [updated 4 April 2019]. 


 2. The Hydrozid® canister should be stored upright, not in sunlight and in temperatures below 50°C


Source: About Hydrozid®HYZ-EN-FACS-7-1 February 2022.pdf

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